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Kinetic mode-based dose (KM dose) vs. gene expression-based dose (GE dose). This figure shows the relationship between GE dose from the best-fit model (Eq. 2) and the KM dose using the retention function (Eq. 1). KM dose and GE dose are collinear (R2 = 0.395, P = 0.016) and represent similar prediction qualities for measuring absorbed dose from a patient.
