Table 1.
Characteristics of SESSA Participants, 870 men aged 40–79 years (2006–2008)
| Characteristic | Quartile of total LDL-P
|
|||
|---|---|---|---|---|
| 1 (297 – 1002 nmol/L) | 2 (1003–1259 nmol/L) | 3 (1260 – 1534 nmol/L) | 4 (1535 – 3156 nmol/L) | |
| Age, years | 64.2 ± 9.5 | 63 ± 10.4 | 63.4 ± 10.7 | 62.6 ± 9.4 |
| Bodymass index, kg/m2 | 22 ± 2.7 | 23.1 ± 2.8 | 23.9 ± 2.9 | 24.4 ± 3 |
| SBP, mmHg | 135 ± 19 | 134 ± 20 | 137 ± 20 | 138 ± 19 |
| Alcohol intake (g/day) | 34.2 ± 33.6 | 20.7 ± 21.3 | 21.9 ± 27.9 | 19.7 ± 25.3 |
| Hypertension, % | 50.7 | 47.5 | 51.4 | 54.6 |
| Current smoker, % | 32.3 | 33.8 | 31.9 | 35.8 |
| Diabetes, % (Type 2) | 15.7 | 16.4 | 19.4 | 21.6 |
| EBCT, % | 71 | 69.4 | 64.4 | 71.6 |
| Triglyceride, mmol/L | 1.3 ± 1.15 | 1.28 ± 0.93 | 1.39 ± 0.59 | 1.61 ± 0.85 |
| LDL-C, mmol/L | 2.41 ± 0.54 | 3.1 ± 0.49 | 3.41 ± 0.49 | 4.11 ± 0.62 |
| HDL-C, mmol/L | 1.76 ± 0.5 | 1.63 ± 0.44 | 1.43 ± 0.39 | 1.31 ± 0.29 |
| HDL-P, μmol/L | 36.3 ± 7.9 | 34.6 ± 6.3 | 33.5 ± 6.3 | 32.6 ± 5.6 |
| Small LDL-P, nmol/L | 171 ± 192 | 350 ± 256 | 620 ± 312 | 984 ± 340 |
| Large LDL-P, nmol/L | 528 ± 240 | 676 ± 284 | 652 ± 317 | 674 ± 309 |
| LDL Size (mean), nm | 21.2 ± 0.5 | 21.1 ± 0.5 | 20.8 ± 0.5 | 20.6 ± 0.5 |
| Non-HDL-C, mmol/L | 2.96 ± 0.66 | 3.67 ± 0.54 | 4.06 ± 0.53 | 4.84 ± 0.69 |
| LDL-C/HDL-C | 1.5 ± 0.5 | 2 ± 0.5 | 2.5 ± 0.6 | 3.3 ± 0.8 |
| Total-C/HDL-C | 2.9 ± 0.8 | 3.4 ± 0.8 | 4 ± 0.8 | 4.9 ± 1 |
| cIMT, μm | 800 ± 167 | 818 ± 183 | 852 ± 196 | 867 ± 182 |
| CAC (Median), Agatston † | 2.3 [0, 65] | 3.6 [0, 59] | 7.7 [0, 104] | 10 [0, 58] |
Values are mean ± SD or % (as indicated).
P-values for trend (P trend) of continuous and categorical variables were obtained using linear regression and logistic regression (for presence of characteristic), respectively, per 1 unit increase in LDL-P.
†
CAC values are displayed as median [25th percentile, 75th percentile]. P value was obtained for presence of CAC (>0) per 1 unit increase in LDL-P.
SBP = systolic blood pressure, EBCT = electron-beam computed tomography, HDL-P = high-density lipoprotein particle, LDL-P = low-density lipoprotein, Total-C = total cholesterol, cIMT= carotid intima-media thickness, CAC = coronary artery calcification.