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. 2016 Nov 1;222:1012–1018. doi: 10.1016/j.ijcard.2016.07.170

Table 3.

Relative risk (95% group-specific confidence interval [g-sCI]) of incident coronary heart disease and stroke in parous women, by reported history of hypertension during pregnancy and treatment for hypertension at baseline.

Incident vascular disease (ICD-10) Hypertension during pregnancy Being treated for hypertension at baseline No. with outcome Relative risk (95% g-sCI)
Coronary heart disease (I20 to I25)
No No 33,884 1.00 (0.99 to 1.01)
Yes No 8999 1.17 (1.14 to 1.19)
No Yes 12,696 1.61 (1.59 to 1.64)
Yes Yes 12,582 1.78 (1.76 to 1.82)



Ischaemic stroke (I63)
No No 4077 1.00 (0.97 to 1.03)
Yes No 1056 1.18 (1.11 to 1.25)
No Yes 1707 1.77 (1.69 to 1.86)
Yes Yes 1525 1.86 (1.76 to 1.96)



Haemorrhagic stroke (I60 to I62)
No No 3184 1.00 (0.96 to 1.04)
Yes No 760 1.09 (1.02 to 1.18)
No Yes 980 1.60 (1.50 to 1.71)
Yes Yes 778 1.48 (1.38 to 1.59)

ICD-10 — International Classification of Diseases, 10th Revision; relative risks are hazard ratios estimated using Cox regression with age as the underlying time variable, stratified by region of recruitment, and adjusted for smoking, socioeconomic status, exercise, alcohol intake, body mass index, parity, ever use of hormone replacement therapy, treatment for diabetes, and treatment for hypercholesterolaemia at baseline; reference group: no history of hypertensive pregnancy and not on anti-hypertensive treatment at baseline.