Plot of liver lesion volume (in cubic millimeters) as a function of laser fluence 24 hours after WST11 VTP. At 100 mW (n = 15; mean, 767.5 mm3; median, 738.85 mm3; IQR, 681.45–834.03 mm3), 200 mW (n = 12; mean, 1204.03 mm3; median, 1227.62 mm3; IQR, 1081.65–1294.91 mm3), and 415 mW (n = 18; mean, 2209.84 mm3; median, 2204.01 mm3; IQR, 1957.35–2443.12 mm3), higher fluences resulted in larger lesion volumes. * = statistical significance (P < .0001 with the Mann-Whitney rank sum test).