Fig. S2.

Data are from HeLa human datasets (A, C, E, and G) B and (B, D, F, and H) P. (A and B) Frequency of replicons in each cohort, defined according to the following size ranges: <10³ bp, XS; 10³ to 10⁴ bp, S; 10⁴ to 10⁵ bp, M; 10⁵ to 10⁶ bp, L; and >10⁶ bp, XL. (C and D) Probability of DFS in each cohort of the replicons. (E and F) Higher-resolution plot of probability of DFS at the transition from M to L gap cohorts contributing most toward the P(DFS); red bars show the bins with maximum P(DFS) in respective datasets. (G and H) Theoretical frequency distribution of replicons inferred from E and F are presented in blue; gray shows the actual frequency distribution in those bins in the data, and red highlights the red bins in E and F.