Fig. 5.

Evolution of Aβ40 and Aβ42 under our optimized low DPC micelle conditions. After incubation for 24 h at 37 °C, Aβ40 aggregates into amyloid fibrils (Upper), whereas Aβ42 assembles into specific pore-forming β-barrel oligomers, βPFOs_Aβ42 (Lower). (Scale bar, 100 nm.)