Table 1.
Pre-ART Characteristics of Individuals by Infection Status
| Characteristic | Infection Status |
||
|---|---|---|---|
| All (n = 3097) | HIV Monoinfected (n = 2870) | HIV/HBV Coinfected (n = 227) | |
| Female gender (n [%]) | 2078 (77.1) | 1960 (68.3) | 118 (52.0) |
| Pregnanta (n [%]) | 122 (7.1) | 118 (7.3) | 4 (4.0) |
| Age (median [IQR]), years | 38.0 (31.0–45.6) | 38.1 (31.8–45.6) | 37.0 (31.7–45.4) |
| Alcohol useb (n [%]) | 730 (25.2) | 671 (24.9) | 60 (28.2) |
| Heavy drinkersc (n [%]) | 14 (7.4) | 13 (7.6) | 1 (5.6) |
| BMId (median [IQR]), kg/m2 | 21.0 (18.9–23.4) | 21.0 (18.9–23.5) | 20.5 (18.3–23.9) |
| ART naive (n [%]) | 344 (11.1) | 328 (11.4) | 16 (7.1) |
| ART regimen at initiatione (n [%]) | |||
| 3TC monotherapy | 1463 (53.1) | 1355 (53.3) | 108 (51.2) |
| TDF + 3TC | 645 (23.4) | 584 (23.0) | 61 (28.9) |
| TDF + FTC | 454 (16.5) | 422 (16.6) | 32 (15.2) |
| Other | 191 (6.9) | 181 (7.1) | 10 (4.7) |
| WHO stage at ART startf (n [%]) | |||
| 1 or 2 | 1415 (56.6) | 1310 (56.8) | 105 (54.4) |
| 3 or 4 | 1084 (43.4) | 996 (43.2) | 88 (45.6) |
| CD4 count baselineg (median [IQR]), cells/µL | 215 (89–404) | 218 (90–405) | 185 (65–365) |
| CD4 count baselineh (median [IQR]), % | 12 (5–21) | 12 (5–21) | 12 (4–19) |
| CD4 count pre-ARTi (median [IQR]), cells/µL | 185 (84–302) | 185 (85–303) | 183 (63–296) |
| CD4 count pre-ARTj (median [IQR]), % | 10 (4–18) | 10 (4–18) | 10 (4–18) |
| Use of antituberculous drugsk (n [%]) | 86 (2.8) | 77 (2.7) | 9 (4.0) |
| PLT < 150 × 109/Ll (n [%]) | 179 (10.5) | 154 (9.9) | 25 (17.9) |
| PLT (median [IQR]), 109/L | 250 (183–322) | 252 (186–323) | 220 (159–307) |
| ASTm (median [IQR]), U/L | 53 (29–92) | 53 (29–93) | 56 (32–86) |
Abbreviations: APRI, aspartate aminotransferase-to-platelet ratio; ART, antiretroviral therapy; BMI, body mass index; FTC, emtricitabine; HBV, hepatitis B infection; HIV, human immunodeficiency virus; IQR, interquartile range; PLT, platelet; TDF, tenofovir disoproxil fumarate; WHO, World Health Organization; 3TC, lamivudine.
a Pregnancy status was available for 1728 individuals.
b Information on alcohol consumption at baseline was available for 2903 individuals.
c Alcohol amounts were available for 190 current drinkers individuals.
d BMI was available for 2353 individuals.
e ART regimen at initiation was available for 2753 individuals.
f WHO stage at ART initiation was available for 2499 individuals.
g CD4 cell count at baseline was available for 2189 individuals.
h CD4% at baseline was available for 2119 individuals.
i CD4 cell count at ART initiation was available for 2127 individuals.
j CD4% at ART initiation was available for 2074 individuals.
k Use of antituberculous drugs was available for 3097 individuals.
l Platelet count was available for 2993 individuals.
m AST was available for 2993 individuals.