Table 5. SNP differences between 198.1 (non-clinical North American agricultural isolates) and 198.2 (human clinical isolates).
The reference genome for this analysis is the chromosome of S. Kentucky CVM29188.
| Locus Tag in CVM N51290 | Locus Tag in CVM29188 | Annotation a | Genome Position a | nt 198.1 | nt 198.2 | Substitution b | aa 198.1 | aa 198.2 | aa Position |
|---|---|---|---|---|---|---|---|---|---|
| AEX15_00985 | SeKA_A0118 | putative cytoplasmic protein | 112694 | A | G | NS | Asn | Ser | 215 |
| AEX15_01465 | SeKA_A0272 | ABC transporter ATP-binding protein | 259861 | G | A | S | Asn | Asn | 352 |
| AEX15_07125 | SeKA_A0450 | outer membrane protein F | 449431 | G | A | S | Ala | Ala | 310 |
| intergenic | 511489 | G | A | ||||||
| intergenic | 528058 | C | G | ||||||
| intergenic | 768380 | G | T | ||||||
| intergenic | 932324 | T | C | ||||||
| AEX15_09820 | SeKA_A1028 | Nitrate reductase alpha subunit | 986092 | C | A | NS | Ser | Tyr | 249 |
| AEX15_09905 | SeKA_A1046 | virulence factor SrfB | 1006926 | C | T | S | Asn | Asn | 389 |
| AEX15_10005 | SeKA_A1065 | PTS system, IIc component | 1028557 | T | G | NS | Val | Gly | 232 |
| AEX15_10580 | SeKA_A1172 | phosphatidylglycerophosphatase B | 1132142 | T | C | NS | Thr | Ala | 184 |
| AEX15_10645 | SeKA_A1188 | anthranilate synthase component I | 1148000 | C | T | NS | Pro | Ser | 225 |
| AEX15_11230 | SeKA_A1320 | hypothetical protein | 1268383 | G | C | NS | Gly | Ala | 47 |
| AEX15_11825 | SeKA_A1435 | aspartyl-tRNA synthetase | 1376156 | C | T | NS | Ala | Thr | 273 |
| AEX15_11880 | SeKA_A1448 | flagellar protein FlhE | 1388508 | T | C | S | Leu | Leu | 624 |
| AEX15_11945 | SeKA_A1461 | transcriptional activator FlhD | 1402136 | G | T | S | Ser | Ser | 4 |
| AEX15_12480 | SeKA_A1563 | arsenical pump-driving ATPase | 1479380 | A | G | NS | Leu | Ser | 578 |
| AEX15_13315 | SeKA_A1750 | beta-D-glucoside glucohydrolase | 1662011 | G | A | S | Thr | Thr | 560 |
| AEX15_13615 | SeKA_A1814 | nucleoid-associated protein NdpA | 1730145 | T | C | NS | Asn | Asp | 136 |
| AEX15_13770 | SeKA_A1846 | DNA gyrase subunit A (gyrA) | 1764089 | G | A | NS | Ser | Phe | 83 |
| AEX15_13940 | SeKA_A1884 | O-succinylbenzoate synthase | 1805065 | C | A | NS | Glu | Asp | 44 |
| AEX15_15785 | SeKA_A2190 | DNA repair protein RecO | 2129001 | T | C | NS | Lys | Glu | 156 |
| AEX15_21540 | SeKA_A2229 | phospho-2-dehydro-3-deoxyheptonate aldolase | 2169354 | G | A | S | Asn | Asn | 149 |
| AEX15_21995 | SeKA_A2343 | murein hydrolase effector LrgB | 2282024 | G | A | S | Gly | Gly | 38 |
| AEX15_22185 | SeKA_A2383 | putative type III secretion system effector protein OrgC | 2317497 | G | A | NS | Ser | Leu | 98 |
| AEX15_22530 | SeKA_A2451 | sulfate adenylyltransferase subunit 1 | 2379190 | A | C | NS | Ile | Ser | 339 |
| intergenic | 2476378 | G | A | ||||||
| AEX15_04160 | SeKA_A2564 | nickel/cobalt efflux protein RcnA | 2496525 | C | T | NS | Pro | Ser | 31 |
| intergenic | 2497451 | C | G | ||||||
| AEX15_04380 | SeKA_A2619 | D-erythrose-4-phosphate dehydrogenase | 2542815 | G | A | NS | Pro | Ser | 224 |
| AEX15_04910 | SeKA_A2749 | DNA topoisomerase IV subunit A (parC) | 2654521 | C | A | NS | Ser | Ile | 80 |
| intergenic | 2760667 | C | A | ||||||
| AEX15_03530 | SeKA_A3124 | cytoplasmic protein | 2998220 | G | A | S | Thr | Thr | 395 |
| AEX15_02625 | SeKA_A3321 | putative glucarate transporter | 3208206 | T | A | NS | Leu | Gln | 355 |
| AEX15_02555 | SeKA_A3336 | ADP-heptose—LPS heptosyltransferase | 3221877 | G | A | S | Pro | Pro | 122 |
| AEX15_02175 | SeKA_A3395 | PTS sorbose transporter subunit IIC | 3280995 | C | T | NS | Gly | Asp | 241 |
| AEX15_14010 | SeKA_A3451 | trimethylamine N-oxide reductase I catalytic subunit | 3334071 | G | A | S | Cys | Cys | 320 |
| AEX15_14230 | SeKA_A3482 | phosphate transporter permease subunit PstC | 3369116 | G | T | NS | Pro | His | 74 |
| AEX15_14255 | SeKA_A3487 | glucosamine—fructose-6-phosphate aminotransferase | 3375283 | T | C | NS | Ile | Val | 490 |
| AEX15_20905 | SeKA_A3529 | threonine dehydratase | 3421216 | G | A | S | Ala | Ala | 446 |
| AEX15_21030 | SeKA_A3553 | putative common antigen polymerase | 3445490 | G | A | S | Leu | Leu | 125 |
| AEX15_21080 | SeKA_A3565 | porphobilinogen deaminase | 3453638 | G | T | NS | Asp | Glu | 117 |
| AEX15_21220 | SeKA_A3595 | chondroitin sulfate/heparin utilization regulation protein | 3480727 | C | T | S | Asn | Asn | 103 |
| AEX15_21260 | SeKA_A3603 | sec-independent translocase | 3489186 | C | T | NS | Pro | Ser | 142 |
| AEX15_21305 | SeKA_A3612 | proline dipeptidase | 3500226 | C | T | S | Ser | Ser | 179 |
| intergenic | 3575800 | C | A | ||||||
| AEX15_21420 | SeKA_A3805 | thiamine-phosphate pyrophosphorylase | 3686081 | C | A | NS | Ala | Ser | 57 |
| AEX15_18585 | SeKA_A3887 | LexA repressor | 3764969 | C | T | S | Ser | Ser | 60 |
| intergenic | 3770533 | C | A | ||||||
| AEX15_18425 | SeKA_A3921 | Na+/H+ antiporter | 3813232 | G | A | S | Ser | Ser | 30 |
| intergenic | 3829881 | C | T | ||||||
| intergenic | 3832063 | T | A | ||||||
| intergenic | 3896075 | C | T | ||||||
| AEX15_17850 | SeKA_A4040 | putative cytoplasmic protein | 3929069 | T | C | S | Thr | Thr | 54 |
| intergenic | 4002925 | G | A | ||||||
| AEX15_20245 | SeKA_A4293 | chitinase | 4165915 | A | G | S | Val | Val | 533 |
| AEX15_20105 | SeKA_A4321 | isoleucyl-tRNA synthetase | 4192511 | C | A | S | Thr | Thr | 62 |
| AEX15_17125 | SeKA_A4346 | carnitine operon protein CaiE | 4219742 | C | T | NS | Glu | Lys | 128 |
| intergenic | 4233585 | C | A | ||||||
| AEX15_16055 | SeKA_A4409 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase | 4286504 | T | C | NS | Ser | Pro | 265 |
| AEX15_16220 | SeKA_A4445 | hypothetical protein | 4325107 | A | G | S | Gly | Gly | 137 |
| AEX15_16390 | SeKA_A4481 | putative fimbrial outer membrane usher protein | 4359640 | G | T | NS | Leu | Met | 704 |
| intergenic | 4463447 | T | C | ||||||
| AEX15_22970 | SeKA_A4665 | fimbrial outer membrane usher protein StbC | 4548312 | A | C | NS | Val | Gly | 119 |
| AEX15_06235 | SeKA_A4762 | 2-aminoethylphosphonate transport system permease PhnU | 4645904 | A | G | NS | Ile | Thr | 92 |
| AEX15_06585 | SeKA_A4840 | copper exporting ATPase | 4725203 | A | G | S | Ser | Ser | 111 |
a = Position/annotation in S. Kentucky CVM29188 (accession no. ABAK02000001.1)
b = S(synonymous), NS(nonsynonymous)