Fig 6. Variations in microbial genera composition and abundance of xenobiotic metabolizing enzymes across different age groups.

Specific abundance profile, representing contribution of each genus in harbouring xenobiotic metabolizing enzymes, in each sample was generated. Only those genera were considered which were present in minimum of 30% of samples belonging to at least one age group. Median values of each microbial genus for each region was calculated and ranked within each age group, and plotted as heat map. There is a differential as well as specific microbial composition in different age groups. While some microbial genera were found to have similar abundance in all the age groups, some showed age specific preferences. Age-specific clustering pattern was also observed. Kruskal-Wallis H test was performed among groups for each genera and significant genera (p-value <0.05) have been reported.