Table 4. Survival outcomes.

	Univariable analysis			Multivariable analysis
	HR	95% CI	P	HR	95% CI	P
MCM1	0.784	0.509–1.207	0.270
MCM2	1.786	1.154–2.734	0.009	1.322	0.700–2.498	0.389
MCM3	1.16	0.754–1.783	0.500
MCM4	1.805	1.159–2.809	0.009	1.240	0.684–2.248	0.478
MCM5	1.349	0.876–2.076	0.174	1.126	0.687–1.845	0.639
MCM6	1.353	0.880–2.079	0.169	0.565	0.309–1.035	0.065
MCM7	1.201	0.780–1.850	0.405
MCM8	1.895	1.227–2.928	0.004	1.707	1.047–2.863	0.032
MCM9	1.108	0.720–1.707	0.640
MCM10	1.818	1.176–2.811	0.007	1.588	0.881–2.863	0.124
Age	1.456	0.942–2.250	0.091	1.448	0.917–2.288	0.112
Gender	0.934	0.608–1.434	0.755
HS	1.556	0.990–2.445	0.055	1.172	0.725–1.895	0.517
N stage	2.001	1.193–3.358	0.009	1.169	0.358–2.816	0.796
T stage	2.396	1.186–4.838	0.015	1.383	0.621–3.080	0.427
TMN stage	2.323	1.333–4.046	0.003	2.052	0.557–7.554	0.280

CI, confidence interval; HR, hazard ratio; HS, Histology stage.