Table 6. SNPs with Strongest Association with Type 2 Diabetes in the Framingham Heart Study.
| P-value Based on | ||||||||
|---|---|---|---|---|---|---|---|---|
| SNP | Chr | Position | Nearest Gene | CERAMIC | MASTOR | EMMAX | MQLS-LOG | MQLS-LIN |
| rs13116548 | 4 | 169874620 | PALLD | 1.3e-05 | 2.6e-05 | 7.8e-05 | 2.7e-05 | 5.2e-05 |
| rs1548315 | 4 | 169841518 | PALLD | 1.3e-05 | 2.5e-05 | 5.8e-05 | 2.9e-05 | 5.2e-05 |
| rs6817551 | 4 | 169829345 | PALLD | 1.9e-05 | 3.6e-05 | 4.7e-05 | 4.7e-05 | 8.0e-05 |
| rs11733251 | 4 | 169881917 | CBR4 | 1.5e-05 | 2.7e-05 | 4.7e-05 | 2.9e-05 | 4.9e-05 |
| rs2331450 | 4 | 169901225 | CBR4 | 1.6e-05 | 2.8e-05 | 5.9e-05 | 3.2e-05 | 5.2e-05 |
| rs10518037 | 4 | 169899023 | CBR4 | 1.7e-05 | 2.9e-05 | 5.9e-05 | 3.4e-05 | 5.6e-05 |
| rs1531254 | 4 | 169881245 | CBR4 | 1.7e-05 | 3.2e-05 | 5.6e-05 | 3.1e-05 | 5.4e-05 |
| rs1870306 | 4 | 169923672 | CBR4 | 1.9e-05 | 3.1e-05 | 8.9e-05 | 3.0e-05 | 4.6e-05 |
| rs17083935 | 9 | 83326808 | TLE1 | 1.4e-05 | 1.7e-05 | 2.3e-05 | 3.9e-05 | 5.8e-05 |
| rs12004598 | 9 | 83354770 | TLE1 | 1.7e-05 | 2.0e-05 | 4.9e-05 | 3.4e-05 | 5.0e-05 |
| rs17083941 | 9 | 83327608 | TLE1 | 2.0e-05 | 2.6e-05 | 5.7e-05 | 5.3e-05 | 8.0e-05 |
| rs4506565 | 10 | 114756041 | TCF7L2 | 1.7e-07 | 4.4e-08 | 1.3e-07 | 3.0e-07 | 1.0e-07 |
| rs7901695 | 10 | 114754088 | TCF7L2 | 3.1e-07 | 9.2e-08 | 5.4e-07 | 4.5e-07 | 1.6e-07 |
| rs12243326 | 10 | 114788815 | TCF7L2 | 1.0e-06 | 4.6e-07 | 3.8e-06 | 2.2e-06 | 1.2e-06 |
| rs4132670 | 10 | 114767771 | TCF7L2 | 1.3e-06 | 3.1e-07 | 1.8e-06 | 2.6e-06 | 8.8e-07 |
| rs7488766 | 12 | 132665596 | GALNT9 | 1.5e-05 | 6.3e-06 | 3.4e-06 | 2.6e-05 | 1.6e-05 |
| rs11874767 | 18 | 3952917 | DLGAP1 | 9.5e-06 | 1.8e-05 | 3.3e-05 | 3.5e-05 | 6.3e-05 |
Bold indicates the smallest p-value for each SNP. MIM numbers of genes not mentioned in the text: PALLD (MIM 608092), CBR4 (No MIM number), DLGAP1 (MIM 605445).