Representative load-displacement curves of female mice fed the high-fat and control diets (A). Effects in female mice fed high-fat and control diets for yield load (B), max load (C), stiffness (D), total displacement (E), post-yield displacement (F). Values are means ± SE; p-values represent main effect of fat. Sample size is shown in parenthesis. Mice fed the high-fat diets had increased femoral biomechanical performance values for yield load, max load, and stiffness compared to mice fed the control diets. Mice fed the high-fat diets had reduced femoral biomechanical performance values for total displacement and post-yield displacement compared to mice fed the control diets.