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Model to show how increase in microtubule ends relates to microtubule severing. Before dendrite injury relatively few long microtubules are present in the dendrites, so few EB1 comets (ovals) are observed. Activation of fidgetin in the injured dendrite could cut the long microtubules into shorter ones, with each piece now having a dynamic plus end. This increase in number of growing plus ends precedes beading of the entire dendrite (right panel) by 4–5 h.
