Figure 6.
Restoration of bone mass over 12 months of antiresorptive therapy in the distal radius of women with PMO.
Notes: (A) Declining porosity in the compact-appearing cortical bone. (B) Increasing trabecular bone mass. Modeling studies show strength in the distal radius is closely tied to cortical structure, including thickness and porosity. Reprinted from Bone, 59, Zebaze RM, Libanati C, Austin M, et al, Differing effects of denosumab and alendronate on cortical and trabecular bone, 173–179.71 Copyright 2015, with permission from Elsevier.
Abbreviations: PMO, postmenopausal osteoporosis; BV/TV, bone volume over total volume.