Table 1.

Fulfilled diagnostic criteria of dependence according to DSM-IV-TR of the individual substances consumed by the patient

Substance	Tolerance	Withdrawal	Use despite harm	Larger/longer use than intended	Unsuccessful desire/effort to reduce use	Time to obtain substance or recover from effects	Reduction of social, occupational, or recreational pursuits
Cannabinoid	x	–	x	x	x	x	x
Nicotine	x	x	x	x	–	–	–
Nitrous oxide	x	–	x	x	–	x	x

Note: Diagnostic criteria of dependence according to DSM-IV-TR19 of the individual substances consumed by the patient. An “x” represents fulfillment and “–” absence of the criterion.