Table 2: Population with actionable genotypes for drugs within medication decision support system.
Gene | Drug | No. (%) of participants (n = 185) |
---|---|---|
CYP2C19 | Citalopram, escitalopram, esomeprazole, lansoprazole, omeprazole, pantoprazole, sertraline | 50 (27.0) |
CYP2C19 | Clopidogrel | 63 (34.0) |
SLCO1B1 | Simvastatin | 53 (28.6) |
CYP2C9 | Celecoxib, flurbiprofen | 5 (2.7) |
CYP2C9 | Warfarin | 67 (36.2) |
VKORC1 | Warfarin | 147 (79.4) |
G6PD | Sulfamethoxazole | 0 (0) |
HLA-B*58:01 | Allopurinol | 7 (3.8) |
CYP2D6 | Metoprolol, oxycodone, propafenone, tramadol, venlafaxine | 91 (49.2) |
CYP2D6 | Codeine | 18 (9.7) |