FIGURE 6.
Reversal of NF-κBp65 DNA binding activity levels associated with DNP/2DG treatment by autophagy inhibitors. Reversal in NF-κBp65 DNA binding activity following treatment with autophagy inhibitors 3-methyladenine (3-MA), chloroquine (CQ), and Bafilomycin-A1 (Baf). Means and standard deviations of three independent experiments are provided. For all inhibitors, NF-κBp65 DNA binding activity is significantly reduced if compared to the DNP/2DG treated sample (t-test, p < 0.005).