Table 2. The annual distribution of causative bacteria in bacteremia of febrile neutropenic children.
| Bacteria | Whole period | 2010 | 2011 | 2012 | 2013 | 2014 | P-value | |
|---|---|---|---|---|---|---|---|---|
| GNB | Klebsiella spp. | 56 (16.7) | 4 (7.5) | 13 (22.0) | 16 (20.5) | 12 (14.1) | 11 (18.0) | 0.222 |
| Escherichia coli | 55 (16.4) | 12 (22.6) | 7 (11.9) | 16 (20.5) | 13 (15.3) | 7 (11.5) | 0.341 | |
| Pseudomonas aeruginosa | 28 (8.3) | 1 (1.9) | 8 (13.6) | 8 (10.3) | 7 (8.2) | 4 (6.6) | 0.229 | |
| Enterobacter spp. | 11 (3.3) | 0 (0.0) | 2 (3.4) | 1 (1.3) | 7 (8.2) | 1 (1.6) | 0.042 | |
| Acinetobacter baumannii | 8 (2.4) | 3 (5.7) | 0 (0.0) | 2 (2.6) | 2 (2.4) | 1 (1.6) | 0.400 | |
| Other GNB | 23 (6.8) | 0 (0.0) | 4 (6.8) | 5 (6.4) | 9 (10.6) | 5 (8.2) | 0.202 | |
| Total of GNB | 181 (53.9) | 20 (37.7) | 34 (57.6) | 48 (61.5) | 50 (58.8) | 29 (47.5) | 0.049 | |
| GPB | Viridans streptococci | 87 (25.9) | 15 (28.3) | 16 (27.1) | 20 (25.6) | 18 (21.2) | 18 (29.5) | 0.807 |
| CNS | 26 (7.7) | 6 (11.3) | 4 (6.8) | 3 (3.8) | 6 (7.1) | 7 (11.5) | 0.415 | |
| Enterococcus spp. | 20 (6.0) | 4 (7.5) | 3 (5.1) | 4 (5.1) | 4 (4.7) | 5 (8.2) | 0.878 | |
| Staphylococcus aureus | 7 (2.1) | 2 (3.8) | 1 (1.7) | 0 (0.0) | 3 (3.5) | 1 (1.6) | 0.497 | |
| Others GPB | 15 (4.5) | 6 (11.3) | 1 (1.7) | 3 (3.8) | 4 (4.7) | 1 (1.6) | 0.087 | |
| Total of GPB | 155 (46.1) | 33 (62.3) | 25 (42.4) | 30 (38.5) | 35 (41.2) | 32 (52.5) | 0.049 | |
| Total | 336 (100.0) | 53 (100.0) | 59 (100.0) | 78 (100.0) | 85 (100.0) | 61 (100.0) | ||
Data are numbers (%).
GNB, gram-negative bacteria; GPB, gram-positive bacteria; CNS, coagulase-negative staphylococci.