Table 4. Independent risk factors for mortality of patients with severe sepsis or septic shock treated with surviving sepsis campaign bundles by Cox’s regression analysis.

Variables	Odds ratio (95% CI)	P-value
7-day mortality
Age	1.020 (0.958–1.085)	0.543
Lactate	1.286 (1.016–1.627)	0.036
eGFR	0.953 (0.913–0.996)	0.032
Antithrombin III	0.967 (0.926–1.009)	0.123
Central venous pressure	1.057 (0.909–1.229)	0.473
APACHE II score	1.127 (0.992–1.281)	0.065
28-day mortality
Age	1.019 (0.967–1.074)	0.483
Lactate	1.346 (1.083–1.673)	0.008
eGFR	0.973 (0.943–1.004)	0.084
Antithrombin III	0.976 (0.941–1.013)	0.197
Central venous pressure	1.005 (0.881–1.146)	0.946
APACHE II score	1.153 (1.029–1.293)	0.014

Per one increase in age, level, pressure, or score.

eGFR, estimated glomerular filtration rate; APACHE, acute physiology and chronic health evaluation.