Table 3.
Effect of LCB on the levels of IL-6, TNF-α, and CRP in mice subjected to CCl4-induced hepatotoxicity (values are presented as means±SD, n = 8)
| Groups | IL-6 (pg/ml) | TNF-α (ng/l) | CRP (μg/l |
|---|---|---|---|
| Control | 72.52 ± 3.14 | 266.06 ± 18.46 | 1079.07 ± 109.65 |
| CCl4 | 110.95 ± 7.11## | 469.83 ± 24.93## | 2171.51 ± 206.39## |
| 1 mg/kg LCB | 108.80 ± 2.20 | 419.63 ± 41.88 | 1958.57 ± 61.03 |
| 5 mg/kg LCB | 93.55 ± 0.93* | 369.63 ± 26.50 | 1858.57 ± 132.53** |
| 25 mg/kg LCB | 82.60 ± 1.09** | 294.63 ± 18.03** | 1583.57 ± 92.41** |
##
P<0.01 compared with the normal control group,
*
P<0.05 and
**
P<0.01