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. 2016 Oct 4;6:34441. doi: 10.1038/srep34441

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) The local TFASA is plotted against the DNA sequence. (b) The TFASA is represented as colors on the structures. The red, white, and blue indicate large, medium, and small TFASAs, respectively. Structural images are generated by VMD.