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. 2016 Oct 4;6:34692. doi: 10.1038/srep34692

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Copyright © 2016, The Author(s)

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(A) Heart tissue of control group: normal myocardial fibers in longitudinal section featuring central nuclei and syncytial arrangement of the fibers; (B) Heart tissue of raw PR group: myocardial fibers with loss of cross striations, not clearly visible nuclei, and inflammatory infiltration; (C) Heart tissue of PRZA group: the histopathological changes were milder than raw PR-treated group; (D) Liver tissue of control group; (E) Liver tissue of raw PR group; (F) Liver tissue of PRZA group; (G) Kidney tissue of control group; (H) Kidney tissue of raw PR group; (I) Kidney tissue of PRZA group. (D–I) Liver and kidney sections of both PR and PRZA groups showed no abnormalities. I. Myocardiocyte necrosis; II. Myocardiocyte rupture; III. Inflammatory infiltration.