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. 2016 Sep 20;6(9):e896. doi: 10.1038/tp.2016.160

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Copyright © 2016 The Author(s)

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EET effects on immobility time in the tail-suspension test across ages. (a). Immobility time in WT and KIV mice at T₁ (SCT/EET) and T₂ (SCT–SCT/EET–SCT). Asterisks on the columns show a significant difference between genotypes. (b). EET effects shown as % SCT across ages at T₁ (top) and at T₂ (bottom). Asterisks on the columns show a significant effect of EET compared with SCT. ED, early-life development; EET, enriched environment treatment; KIV, knock-in BDNF-promoter IV; OA, old adult; SCT, standard condition treatment; WT, wild-type; YA, young adult. *P<0.05, **P<0.01, ***P<0.005. N=11–16.