Table 1.
Patient demographic information for the Optima and Discovery patients investigated
| Age at death Mean ± SD (range) | F/M | |
|---|---|---|
| OPTIMA patients (n) | ||
| Pure LBD (12) | 80.8 ± 6.5 (71–92) | 4/8 |
| Parkinson's disease (2) | 77.5 ± 7.8 (72–83) | 0/2 |
| Mixed LBD/AD (17) | 80.1 ± 6.4 (69–90) | 10/7 |
| AD with incidental LB (13) | 79.8 ± 7.8 (67–91) | 9/4 |
| Pure AD (30) | 77.7 ± 8.6 (61–93) | 17/13 |
| Progressive supranuclear palsy (PSP) (2) | 69.5 ± 3.5 (67–72) | 2/0 |
| Corticobasal degeneration (CBD) (3) | 64.0 ± 10.6 (52–72) | 1/2 |
| Controls (20) | 82.9 ± 6.9 (68–93) | 10/10 |
| Discovery patients (n) | ||
| Parkinson's disease (20) | 65.1 ± 9.1 (42–80) | 6/14 |
| At‐risk RBD patients (3) | 67.6 ± 7.7 (59–74) | 0/3 |
| Controls (15) | 65.8 ± 7.4 (55–83) | 8/7 |