Table 1.
Physiologic data pre‐ and post‐EMST
| Timeline day | Baseline (0) | Post‐sham (60) | Post‐EMST (120) | Change Post‐sham (%) | Change Post‐EMST (%) |
|---|---|---|---|---|---|
| MEP (cm H20) | 56 | 51 | 103 | −9 | +102 |
| CIV (L) | 1.01 | 1.44 | 1.87 | +43 | +30 |
| CrTot | 1 | 2 | 5 | +100 | +150 |
| ALSFRS‐R | 32 | 29 | 30 | −9 | +3 |
|
ALSFRS‐ R Subscores |
R: 10 B: 12 |
R: 10 B: 11 |
R: 12 B: 11 |
R: 0 B: −8 |
R: +20 B: 0 |
Physiologic data over a 4‐month period for respiratory, cough, and global disease progression in a 71‐year‐old male with ALS who participated in a randomized clinical trial. He completed 8 weeks of sham training (Baseline–Post‐sham) followed by 8 weeks of active EMST respiratory training.
MEP, maximum expiratory pressure; CIV, cough inspired volume; CrTot, total coughs produced within an epoch; ALSFRS‐R, ALS functional rating scale‐revised; R, respiratory subscore; B, bulbar subscore; EMST, expiratory muscle strength.