Table 3.
Asymptomatic | Affective | Somatic | Comorbid | |||||||
---|---|---|---|---|---|---|---|---|---|---|
n | % | n | % | n | % | n | % | p-value* | ||
Total | 9914 | 61.6 | 2229 | 13.9 | 2168 | 13.5 | 1722 | 10.7 | ||
Sex | ||||||||||
Male | 5461 | 65.8 | 1199 | 14.5 | 866 | 10.4 | 770 | 9.3 | <0.0001 | |
Female | 4453 | 57.6 | 1030 | 13.3 | 1302 | 16.8 | 952 | 12.3 | ||
Race | ||||||||||
White | 8687 | 61.9 | 1972 | 14.1 | 1885 | 13.4 | 1485 | 10.6 | 0.0005 | |
Black | 618 | 63.6 | 107 | 11.0 | 156 | 16.0 | 91 | 9.4 | ||
Other | 549 | 59.5 | 131 | 14.2 | 113 | 12.3 | 129 | 14.0 | ||
Education | ||||||||||
<High school | 598 | 49.7 | 202 | 16.8 | 189 | 15.7 | 214 | 17.8 | <0.0001 | |
High school | 1930 | 62.2 | 388 | 12.5 | 405 | 13.1 | 378 | 12.2 | ||
Some college | 3411 | 60.1 | 812 | 14.3 | 764 | 13.5 | 685 | 12.1 | ||
≥College graduate | 3653 | 66.6 | 733 | 13.4 | 730 | 13.3 | 372 | 6.8 | ||
Marital Status | ||||||||||
Single | 4897 | 61.8 | 1300 | 16.4 | 904 | 11.4 | 826 | 10.4 | <0.0001 | |
Married/Live as married | 4165 | 65 | 654 | 10.2 | 1022 | 16 | 562 | 8.8 | ||
Divorced/separated | 629 | 49.5 | 220 | 17.3 | 163 | 12.8 | 259 | 20.4 | ||
Household Income | ||||||||||
≤19,999 | 1067 | 48.2 | 364 | 16.4 | 342 | 15.4 | 441 | 19.9 | <0.0001 | |
20,000–39,999 | 1641 | 58.5 | 415 | 14.8 | 408 | 14.5 | 341 | 12.2 | ||
40,000–59,999 | 1670 | 61.4 | 380 | 14.0 | 386 | 14.2 | 283 | 10.4 | ||
60,000–79,999 | 1355 | 65.2 | 281 | 13.5 | 284 | 13.7 | 159 | 7.6 | ||
≥80,000 | 2749 | 69 | 495 | 12.4 | 474 | 11.9 | 268 | 6.7 | ||
Perceived Health Status | ||||||||||
Excellent | 2433 | 82.7 | 258 | 8.8 | 187 | 6.4 | 65 | 2.2 | <0.0001 | |
Very good | 4138 | 69.9 | 811 | 13.7 | 645 | 10.9 | 323 | 5.5 | ||
Good | 2725 | 53.3 | 845 | 16.5 | 865 | 16.9 | 680 | 13.3 | ||
Fair/Poor | 551 | 28.4 | 303 | 15.6 | 449 | 23.2 | 636 | 32.8 | ||
Pain | ||||||||||
Headache | 2049 | 45.3 | 682 | 15.1 | 923 | 20.4 | 869 | 19.2 | <0.0001 | |
Other pain | 356 | 39.6 | 138 | 15.4 | 220 | 24.5 | 185 | 20.6 | ||
No pain | 7239 | 71.4 | 1338 | 13.2 | 958 | 9.4 | 603 | 5.9 | ||
Psychoactive Medication | ||||||||||
Analgesics | ||||||||||
Yes | 759 | 40.9 | 289 | 15.6 | 399 | 21.5 | 411 | 22.1 | <0.0001 | |
No | 9155 | 64.6 | 1940 | 13.7 | 1769 | 12.5 | 1311 | 9.2 | ||
Antidepressants | ||||||||||
Yes | 442 | 31.4 | 283 | 20.1 | 240 | 17.1 | 442 | 31.4 | <0.0001 | |
No | 9472 | 64.8 | 1946 | 13.3 | 1928 | 13.2 | 1280 | 8.8 | ||
Anxiolytics, hypnotics, sedatives | ||||||||||
Yes | 199 | 28.8 | 98 | 14.2 | 156 | 22.5 | 239 | 34.5 | <0.0001 | |
No | 9715 | 63.3 | 2131 | 13.9 | 2012 | 13.1 | 1483 | 9.7 | ||
CNS Stimulants | ||||||||||
Yes | 106 | 43.3 | 43 | 17.6 | 40 | 16.3 | 56 | 22.9 | <0.0001 | |
No | 9808 | 62.1 | 2186 | 13.8 | 2128 | 13.5 | 1666 | 10.6 | ||
Neuroleptics | ||||||||||
Yes | 79 | 27.7 | 45 | 15.8 | 61 | 21.4 | 100 | 35.1 | <0.0001 | |
No | 9835 | 62.5 | 2184 | 13.9 | 2107 | 13.4 | 1622 | 10.3 | ||
Muscle Relaxants | ||||||||||
Yes | 107 | 33.6 | 39 | 12.3 | 79 | 24.8 | 93 | 29.2 | <0.0001 | |
No | 9807 | 62.4 | 2190 | 13.9 | 2089 | 13.3 | 1629 | 10.4 | ||
Diagnosis | ||||||||||
Leukemia | 2723 | 62.0 | 622 | 14.2 | 542 | 12.3 | 506 | 11.5 | 0.0021 | |
CNS tumor | 1614 | 60.9 | 412 | 15.5 | 328 | 12.4 | 298 | 11.2 | ||
Hodgkin lymphoma | 1594 | 61.3 | 341 | 13.1 | 396 | 15.2 | 270 | 10.4 | ||
non-Hodgkin lymphoma | 1013 | 63.6 | 219 | 13.7 | 204 | 12.8 | 158 | 9.9 | ||
Kidney (Wilms) | 737 | 63.5 | 148 | 12.8 | 164 | 14.1 | 111 | 9.6 | ||
Neuroblastoma | 472 | 62.5 | 105 | 13.9 | 116 | 15.4 | 62 | 8.2 | ||
Soft tissue sarcoma | 765 | 63.1 | 164 | 13.5 | 162 | 13.4 | 121 | 10 | ||
Bone cancer | 996 | 59.8 | 218 | 13.1 | 256 | 15.4 | 196 | 11.8 | ||
Diagnosis Decade | ||||||||||
1970–79 | 3322 | 60.7 | 817 | 14.9 | 744 | 13.6 | 593 | 10.8 | 0.0095 | |
1980–89 | 3306 | 62.4 | 753 | 14.2 | 700 | 13.2 | 538 | 10.2 | ||
1990–99 | 3286 | 62.5 | 659 | 12.5 | 723 | 13.7 | 591 | 11.2 | ||
Cancer Treatment | ||||||||||
Antimetabolites | ||||||||||
Yes | 3669 | 60.9 | 857 | 14.2 | 798 | 13.2 | 700 | 11.6 | 0.1092 | |
No | 5168 | 61.3 | 1181 | 14.0 | 1191 | 14.1 | 887 | 10.5 | ||
Anthracyclines | ||||||||||
Yes | 4142 | 62.0 | 830 | 12.4 | 928 | 13.9 | 776 | 11.6 | <0.0001 | |
No | 4607 | 60.6 | 1182 | 15.5 | 1033 | 13.6 | 783 | 10.3 | ||
Alkylating Agents | ||||||||||
Yes | 4369 | 61.0 | 1003 | 14.0 | 990 | 13.8 | 796 | 11.1 | 0.4790 | |
No | 4120 | 62.0 | 941 | 14.2 | 874 | 13.2 | 707 | 10.6 | ||
Steroids | ||||||||||
Yes | 4172 | 60.9 | 990 | 14.4 | 901 | 13.1 | 791 | 11.5 | 0.0485 | |
No | 4800 | 61.5 | 1085 | 13.9 | 1107 | 14.2 | 815 | 10.4 | ||
Radiation | ||||||||||
None | 3807 | 63.0 | 813 | 13.5 | 772 | 12.8 | 650 | 10.8 | <0.0001 | |
Non-cranial | 2622 | 60.0 | 595 | 13.6 | 682 | 15.6 | 474 | 10.8 | ||
Cranial | 2332 | 60.1 | 612 | 15.8 | 491 | 12.7 | 446 | 11.5 | ||
Age and Time | ||||||||||
Mean | SD | Mean | SD | Mean | SD | Mean | SD | p-value | ||
Age at baseline | 27.1 | 5.9 | 26.5 | 5.8 | 27.6 | 6.0 | 27.3 | 5.9 | <0.0001 | |
Age at diagnosis | 9.4 | 5.6 | 9.0 | 5.4 | 9.8 | 5.7 | 9.5 | 5.4 | 0.0001 | |
Time since diagnosis | 17.7 | 4.3 | 17.5 | 4.3 | 17.8 | 4.3 | 17.8 | 4.4 | 0.0633 |
Note. p-values based on chi-square tests for categorical and ANOVA for continuous variables; SD=standard deviation; Frequencies based on number of participants for whom information was available.