Table 5.
Multivariable models predicting survivor distress cluster membership: treatment and sociodemographic factors
| Risk Factor | Comorbid | Somatic | Affective | |||
|---|---|---|---|---|---|---|
| OR | 95%CI | OR | 95%CI | OR | 95%CI | |
| Radiation | ||||||
| None | 1.0 | 1.0 | 1.0 | |||
| Radiation (Cranial vs. none) | 1.06 | 0.93–1.20 | 1.07 | 0.95–1.21 | 1.14 | 1.01–1.28 |
| Radiation (Noncranial vs. none) | 1.00 | 0.87–1.16 | 1.27 | 1.12–1.44 | 1.11 | 0.97–1.26 |
| Chemotherapy | ||||||
| Antimetabolites (yes vs. no) | 1.02 | 0.88–1.19 | 1.19 | 1.03–1.37 | 1.04 | 0.90–1.20 |
| Anthracycline (yes vs. no) | 1.08 | 0.95–1.23 | 0.96 | 0.85–1.09 | 0.72 | 0.64–0.81 |
| Alkylating agents (yes vs. no) | 0.99 | 0.88–1.12 | 1.10 | 0.98–1.23 | 1.16 | 1.04–1.30 |
| Steroids (yes vs. no) | 1.10 | 0.96–1.26 | 0.83 | 0.73–0.94 | 1.02 | 0.89–1.15 |
| Age at diagnosis (per year) | 1.00 | 0.99–1.01 | 1.01 | 1.00–1.02 | 0.98 | 0.97–0.99 |
| Time since diagnosis (per year) | 1.00 | 0.99–1.02 | 1.01 | 1.00–1.02 | 0.98 | 0.97–0.99 |
Note. Adjusted for sex and race. Risk for comorbid, somatic and affective cluster membership referenced to asymptomatic cluster. OR associated with age at diagnosis based on each year older, and time since diagnosis based on each year from diagnosis.