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. Author manuscript; available in PMC: 2017 Nov 15.
Published in final edited form as: J Affect Disord. 2016 Jul 13;205:73–80. doi: 10.1016/j.jad.2016.06.062

Table 3.

Standardized regression coefficients for covariates predicting depressive symptom severity and odds ratios for covariates predicting individual MADRS items.

Covariates
Outcome Episode Status (ref=Euthymic) BP Subtype (ref=BPI)
Age Sex (M=0) Substance Dependence Anxiety Disorder MDE ME MIXE HYPME Age of BP Onset Rapid Cycling BPII NOS Other
Latent Trait (β)
Depressive Symptom Severity −0.08 −0.07 0.02 0.13 0.46 0.04 0.20 0.02 −0.06 0.05 0.00 −0.01 −0.03
MADRS items (OR)
Apparent Sadness 1.02 1.59* 1.20 1.27 2.27* 0.84 1.27 0.54* 1.18 0.99 0.86 0.98 0.79
Reported Sadness 1.02 1.47* 1.26 0.84 2.74* 0.98 1.34 0.69 1.15 1.13 1.16 1.20 0.80
Inner Tension 1.00 1.24 1.17 1.55* 1.34 2.59* 1.87* 1.65 0.93 1.16 1.13 1.39 1.58
Reduced Sleep 1.01 1.24 1.03 1.32 1.20 3.72* 2.77* 3.13* 0.92 1.29 1.13 1.05 0.96
Reduced Appetite 1.00 1.25 1.29 1.23 1.28 1.81* 1.40 1.72 0.99 1.17 0.92 1.07 0.78
Concentration 1.01 1.56* 1.14 1.19 1.85* 1.69 2.42* 2.34* 0.97 1.12 1.08 1.15 1.00
Lassitude 1.01 1.72* 1.17 1.05 1.79* 0.39* 1.02 0.78 1.10 1.16 1.01 0.92 1.11
Inability to Feel 1.01 1.12 1.03 0.98 2.21* 0.64 1.66* 0.74 1.14 1.19 1.20 1.39 0.98
Pessimistic Thgts. 1.01 1.19 1.10 1.07 1.37 0.63 1.25 0.76 1.01 1.11 1.13 1.08 0.85
Suicidal Thoughts 1.01 1.17 1.15 1.16 1.69* 1.28 1.33 0.87 0.97 1.13 1.09 1.06 1.44

Note. Statistically significant (p < 0.01) coefficients are bolded. Statistically significant and clinically significant (i.e., estimated Cohen's D > 0.20) coefficients are starred. ref = reference group for a series of dummy coded covariates. BP = Bipolar. M = Male. MDE = Major Depressive Episode. ME = Manic Episode. MIXE = Mixed Episode. HYPME = Hypomanic Episode. Concentration = Concentration Difficulties. Thgts. = Thoughts.