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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: DNA Repair (Amst). 2016 Sep 1;46:20–28. doi: 10.1016/j.dnarep.2016.08.002

Table 2.

dGC8-N-ABA bypass halftimes of human Y-family polymerases at 37 °C

Polymerase t50(s)a t50bypass(s)b t50bypass/t50
hPolη 0.7 13 19
hPolκ 0.3 7 23
hPolι 200 >10,800 >55
hRev1 1,800 >37,000 >20
a

Calculated as the time required for traversing 50% of undamaged dG.

b

Calculated as the time required for bypassing of 50% of dGC8-N-ABA.