Table 3.
Unadjusted Associations of Environmental Tobacco Smoke Exposure and Active Smoking to Risk of Late-Diagnosis Incident Fibroids in the SWAN Study Population
| a) All Women (n=2575) | b) Restricted to Non-Hispanic White (n=1255) | c) Restricted to African-Americans (n=631) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases | OR | 95%CI Lower |
95%CI Upper |
Cases | OR | 95%CI Lower |
95%CI Upper |
Cases | OR | 95%CI Lower |
95%CI Upper |
||||
| Environmental Tobacco Smoke Exposure | |||||||||||||||
| ≥1 vs. 0 person-hours/week | 512 | 1.29 | 1.08 | 1.55 | * | 251 | 1.18 | 0.91 | 1.52 | 162 | 1.12 | 0.80 | 1.57 | ||
| Active Smoking | |||||||||||||||
| Former Smoker vs. Never | 512 | 0.65 | 0.31 | 1.39 | 251 | 0.36 | 0.09 | 1.45 | 162 | 0.52 | 0.16 | 1.65 | |||
| Current Smoker vs. Never | 512 | 0.82 | 0.63 | 1.07 | 251 | 0.77 | 0.52 | 1.15 | 162 | 0.61 | 0.40 | 0.93 | * | ||
p-values < 0.05 were considered statistically significant.
Unadjusted discrete-time proportional odds models were used to obtain the conditional odds ratio (OR) of incident self-reported diagnosis of fibroids. Time-varying ETS exposure was lagged by 1 follow-up year. All analyses were restricted to women without self-reported fibroids and cancer at baseline.