Table 5.
Association between clinical features of RSA and genotype of miRNA-27a rs895819 A/G and Leptin rs7799039 G/A n (%).
| Genotype | Case group | Severe pregnancy reaction | Abortion time in pregnancy (≥3 months) | Number of abortion (≥3 times) | Duration to next pregnancy (≥6 months) |
|---|---|---|---|---|---|
| miRNA-27a rs895819 | |||||
| AA | 56 (40.7%) | 5 (8.9%) | 2 (3.6%) | 9 (16.1%) | 1 (1.8%) |
| AG + GG | 82 (59.3%) | 23 (28.0%) | 14 (17.1%) | 32 (39.0%) | 13 (4.8%) |
| χ2 | 5.171 | 4.815 | 4.743 | 6.063 | |
| P | 0.023 | 0.028 | 0.029 | 0.014 | |
| Leptinrs7799039 | |||||
| GG | 11 (8.0%) | 6 (54.5%) | 4 (36.4%) | 8 (72.7%) | 5 (45.5%) |
| GA + AA | 127 (92.0%) | 22 (17.3%) | 12 (9.4%) | 33 (26.0%) | 9 (7.1%) |
| χ2 | 4.586 | 4.729 | 4.438 | 10.39 | |
| P | 0.032 | 0.030 | 0.035 | 0.001 | |