Table 3.
Population | Comparison | SDS total (≤6 vs >6) | Item 1 (≤2 vs >2) | Item 2 (≤2 vs >2) | Item 3 (≤2 vs >2) | ||||
---|---|---|---|---|---|---|---|---|---|
OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | ||
All patients | DLX vs SSRI | 1.2 (0.95, 1.53) | 0.119 | 1.2 (0.92, 1.44) | 0.220 | 1.2 (0.95, 1.42) | 0.132 | 1.1 (0.92, 1.37) | 0.270 |
PLB vs SSRI | 0.9 (0.62, 1.32) | 0.613 | 0.6 (0.39, 0.82) | 0.003 | 0.7 (0.48, 0.94) | 0.019 | 0.6 (0.46, 0.88) | 0.007 | |
HAMD‐17 ≤ 22a | DLX vs SSRI | 1.3 (0.94, 1.73) | 0.122 | 1.1 (0.83, 1.48) | 0.494 | 1.2 (0.89, 1.50) | 0.285 | 1.1 (0.83, 1.41) | 0.580 |
PLB vs SSRI | 0.9 (0.60, 1.39) | 0.684 | 0.6 (0.38, 0.87) | 0.009 | 0.6 (0.44, 0.92) | 0.016 | 0.7 (0.45, 0.94) | 0.022 | |
HAMD‐17 > 22a | DLX vs SSRI | 1.1 (0.76, 1.60) | 0.611 | 1.2 (0.86, 1.75) | 0.266 | 1.2 (0.86, 1.60) | 0.317 | 1.2 (0.86, 1.59) | 0.310 |
PLB vs SSRI | 0.9 (0.37, 2.27) | 0.858 | 0.5 (0.22, 1.25) | 0.143 | 0.9 (0.40, 1.83) | 0.693 | 0.6 (0.26, 1.22) | 0.146 |
CI, confidence interval; DLX, duloxetine; HAMD‐17, 17‐item Hamilton Depression Rating Scale; OR, odds ratio; p, p‐value; PLB, placebo; SDS, Sheehan Disability Scale; SSRI, selective serotonin reuptake inhibitor.
Baseline score.