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. 2015 Sep 1;31(1):53–63. doi: 10.1002/hup.2500

Table 3.

Logistical regression analysis of SDS total scores (≤6 vs >6) and SDS items 1, 2 and 3 scores (≤2 vs >2)—data from studies HMAYa, HMAYb, HMCR and HMFT; all randomized patients

Population Comparison SDS total (≤6 vs >6) Item 1 (≤2 vs >2) Item 2 (≤2 vs >2) Item 3 (≤2 vs >2)
OR (95% CI) p OR (95% CI) p OR (95% CI) p OR (95% CI) p
All patients DLX vs SSRI 1.2 (0.95, 1.53) 0.119 1.2 (0.92, 1.44) 0.220 1.2 (0.95, 1.42) 0.132 1.1 (0.92, 1.37) 0.270
PLB vs SSRI 0.9 (0.62, 1.32) 0.613 0.6 (0.39, 0.82) 0.003 0.7 (0.48, 0.94) 0.019 0.6 (0.46, 0.88) 0.007
HAMD‐17 ≤ 22a DLX vs SSRI 1.3 (0.94, 1.73) 0.122 1.1 (0.83, 1.48) 0.494 1.2 (0.89, 1.50) 0.285 1.1 (0.83, 1.41) 0.580
PLB vs SSRI 0.9 (0.60, 1.39) 0.684 0.6 (0.38, 0.87) 0.009 0.6 (0.44, 0.92) 0.016 0.7 (0.45, 0.94) 0.022
HAMD‐17 > 22a DLX vs SSRI 1.1 (0.76, 1.60) 0.611 1.2 (0.86, 1.75) 0.266 1.2 (0.86, 1.60) 0.317 1.2 (0.86, 1.59) 0.310
PLB vs SSRI 0.9 (0.37, 2.27) 0.858 0.5 (0.22, 1.25) 0.143 0.9 (0.40, 1.83) 0.693 0.6 (0.26, 1.22) 0.146

CI, confidence interval; DLX, duloxetine; HAMD‐17, 17‐item Hamilton Depression Rating Scale; OR, odds ratio; p, p‐value; PLB, placebo; SDS, Sheehan Disability Scale; SSRI, selective serotonin reuptake inhibitor.

a

Baseline score.