Table 1.
Theme | Key findings |
---|---|
Adherence | Different biologics have different levels of adherence9 |
Better adherence is observed when the dermatologist clarifies the treatment schedule10 | |
Better adherence is observed when the dermatologist keeps the patient informed and meets the patient's requests10 | |
Decision making | No biological can be considered best for all patients11 |
Patient preference should be a major deciding factor in biological choice11 | |
The dermatologist is the most important source for patient understanding of biologics, followed by research on the internet12 | |
The life course of patients has an impact on treatment strategies13, 14 | |
Fear of adverse effects is an important factor in patient preference11, 15 | |
Quality of life | Treatment strategy has an impact on DLQI16 |
Patients on topical and traditional systemic therapies have higher DLQI scores16, 17 | |
Patients with high DLQI and PASI scores benefit most from biologics18 | |
Skindex‐29, a QoL scoring system, does not correlate with improvements in PASI19 | |
DLQI is an independent predictor of work productivity20 | |
Patient/physician goals | Achieving PASI‐75 leads to improvement of the HRQoL index (lack of direct correlation of PASI with DLQI)21, 22 |
The Patient Benefit Index can be used as goal attainment scaling tool23 | |
Questionnaires | When addressing the patient, the physician should use simple language and improve the patient′s psychological skills24 |
It is important to communicate to the patient:24 | |
(i) That the physician understands the disease | |
(ii) That there is hope of cure | |
(iii) The perception of control | |
Patient‐reported outcomes | A clear definition of patient‐reported outcomes is needed |
Biologics also have a benefit on non‐PASI outcomes3 | |
Satisfaction | Patients with high disease severity need a patient‐centred approach, as they are often dissatisfied with therapy25 |
A study of 1293 patients revealed that topical therapy was significantly associated with least satisfaction; highest satisfaction was seen with biologics5 | |
For satisfaction, patients rated treatment effectiveness as most important, followed by treatment safety and doctor/patient communication5 | |
Patient benefit index | PBI is a suitable instrument for the assessment of the patient‐reported benefit8 |
More tools for understanding parameters of patient benefit and satisfaction are needed26 |
DLQI, dermatology quality of life index; HRQoL, health‐related quality of life; PASI, psoriasis area severity index.