Table 5.
Sensitivity Analysis of the Impact of Vaccine Cost on Total Net Cost of an Infant Routine Pneumococcal Vaccination Program with PCV13 in Malaysia
| Cumulative 10 years |
|||||
|---|---|---|---|---|---|
| No Vaccination | PCV13 vs. No vaccination | ||||
| Vaccine price per dose | n.a. | $55.08 | $44.06 | $33.05 | $22.03 |
| Price as % of base case | n.a. | 100% | 80% | 60% | 40% |
| If 4-doses per course schedule | |||||
| Costs | |||||
| Direct medical excluding vaccination | $ 3,159,743,854 | $ (289,612,306) | $ (289,612,306) | $ (289,612,306) | $ (289,612,306) |
| Vaccination program** | n.a. | $ 1,059,946,438 | $ 858,961,814 | $ 657,922,387 | $ 456,882,959 |
| Non-medical | $ 2,424,145,432 | $ (181,555,052) | $ (181,555,052) | $ (181,555,052) | $ (181,555,052) |
| Net Total Cost Perspective | |||||
| Payer (net medical cost) | $ 3,159,743,854 | $ 770,334,132 | $ 569,349,508 | $ 368,310,081 | $ 167,270,653 |
| Societal | $ 5,583,889,285 | $ 588,779,080 | $ 387,794,456 | $ 186,755,029 | $ (14,284,399) |
| If 3-doses per course schedule | |||||
| Costs | |||||
| Direct medical excluding vaccination | $ 3,159,743,854 | $ (289,612,306) | $ (289,612,306) | $ (289,612,306) | $ (289,612,306) |
| Vaccination program | n.a. | $ 811,659,911 | $ 657,720,804 | $ 503,781,698 | $ 349,842,592 |
| Non-medical | $ 2,424,145,432 | $ (181,555,052) | $ (181,555,052) | $ (181,555,052) | $ (181,555,052) |
| Net Total Cost Perspective | |||||
| Payer (net medical cost) | $ 3,159,743,854 | $ 522,047,605 | $ 368,108,498 | $ 214,169,392 | $ 60,230,286 |
| Societal | $ 5,583,889,285 | $ 340,492,553 | $186,553,446 | $ 32,614,340 | $ (121,324,766) |
Notes. Abbreviations: n.a., not applicable. Numbers in parenthesis ( ) represent cost savings. Societal perspective includes net medical costs.