Table 1.

Cellular response in naked DNA-treated mice during the acute phase of T. cruzi infection

Stimuli	A. In vivo (DTH, mm ± SE)		B. In vitro (Proliferation, cpm ± SE)
Treatment	Against F105	Against Cz	Upon F105	Upon Cz
nEmpty	0.010 ± 0.004	0.041 ± 0.015	859 ± 292	775 ± 408.4
nGM-CSF	0.023 ± 0.014	0.042 ± 0.014	321 ± 111	269 ± 64
nCz	0.096 ± 0.019*	0.102 ± 0.015*	5304 ± 1419*	5214 ± 1785*
nCz+nGM−CSF	0.122 ± 0.013**	0.106 ± 0.020*	10209 ± 3143*	8570 ± 2201**

C3H/HeN mice challenged with a sublethal dose of RA trypomastigotes were treated by intramuscular route with 2 doses of nCz, nGM-CSF or nCz+nGM−CSF. The results represent the media of 7 determinations ± standard error, and are representative of 3 independent experiments. *p << 0.05; **p < 0.01.