Table 2.
Cellular response in Salmonella-treated mice during the acute phase of T. cruzi infection
| Stimuli | A. In vivo (DTH, mm ± SE) |
B. In vitro (Proliferation, cpm ± SE) |
||
|---|---|---|---|---|
| Treatment | Against F105 | AgainstCz | Upon F105 | UponCz |
| SEmpty | 0.018 ± 0.011 | 0.021 ± 0.021 | 85.4 ± 50.7 | 8.2 ± 4.4 |
| SGM-CSF | 0.048 ± 0.024 | 0.020 ± 0.015 | 185.5 ± 99.6 | 5.4± 3.4 |
| SCz | 0.037 ± 0.018 | 0.046 ± 0.019 | 133.1 ± 36.62 | 64.1 ± 51.6 |
| SCz+SGM−CSF | 0.074 ± 0.013* | 0.098 ± 0.018* | 1508 ± 557.2* | 847.2 ± 331.6*** |
C3H/HeN mice challenged with a sublethal dose of RA trypomastigotes were treated by oral route with 2 doses of SCz, SGM-CSF or SCz+SGM−CSF. The results represent the media of 7 determinations ± standard error, and are representative of 3 independent experiments.