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. 2016 Oct 4;11(10):e0163264. doi: 10.1371/journal.pone.0163264

Table 3. Comparison between non-relapsed and relapsed colorectal cancer patients.

Non-relapse N = 250 Relapse N = 48 P
Gender (Male/Female) 144/106 24/24 0.331
Age (year) 64.2±11.0 65.3±12.8 0.546
Maximum tumor size≧5cm 66 (26.4%) 12 (25%) 0.840
Location (rectum/colon) 58/192 19/29 0.018
Depth of tumor invasion 96/154 15/33 0.348
 T (1+2/3+4)
Lymph node metastasis 157/93 27/21 0.392
 N (0/1+2)
Histology (WD+MD/PD) 214/9 45/3 0.392
TNM stage (I-II/III) 157/93 27/21 0.392
Vascular invasion 68 (27.2%) 18 (37.5%) 0.149
Perineural invasion 45 (18.0%) 16 (33.3%) 0.016
Abnormal preoperative CEA level 72 (28.8%) 26 (54.2%) 0.001
Abnormal postoperative CEA level 42 (16.8%) 29 (60.4%) <0.001
Positive biomarker chip 20 (8.0%) 42 (87.5%) <0.001
Mortality 6 (1.6%) 20 (29.5%) <0.001
Follow up (month)
 Median, range 29.6, 7.3–59.8 24.1, 3.0–61.3 0.058
 Mean ± SD 29.5±9.5 26.6±10.6