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. 2016 Oct 4;11(10):e0163264. doi: 10.1371/journal.pone.0163264

Table 4. Factors influencing the relapse estimated by univariate and multivariate logistic regression analyses.

Univariate regression Multivariate regression
Odds ratio (95% CI) P Odds ratio (95% CI) P
Maximum tumor size≧5cm 0.929 (0.456, 1.893) 0.840 - -
Location (rectum/colon) 2.169 (1.134, 4.149) 0.019 1.566 (0.564, 4.348) 0.389
Depth of tumor invasion 1.371 (0.708, 2.657) 0.349 - -
 T (1+2/3+4)
Lymph node metastasis 1.313 (0.703, 2.454) 0.393 - -
 N (0/1+2)
Histology (WD+MD/PD) 1.785 (0.465, 6.851) 0.398 - -
TNM stage (I+II/III) 1.313 (0.703, 2.454) 0.393 - -
Vascular invasion 1.606 (0.841, 3.068) 0.152 - -
Perineural invasion 2.278 (1.152, 4.502) 0.018 2.181 (0.716, 6.644) 0.170
Abnormal preoperative CEA level 2.922 (1.556, 5.488) 0.001 2.538 (0.885, 7.277) 0.083
Abnormal postoperative CEA level 7.559 (3.880, 14.724) <0.001 4.136 (1.455, 11.755) 0.008
Positive biomarker chip 80.500 (30.523, 212.309) <0.001 66.878 (23.229, 192.548) <0.001

95% CI: 95% confidence interval