Fig. 2.
IgG responses towards preS and synthetic preS-derived overlapping peptides. Optical density values (y-axes: OD values at 405 nm) corresponding to IgG levels of rabbits immunized with (a) preS (n = 1), (b) 20 μg of BM32 (n = 2), (c) 40 μg of BM32 (n = 2) or to IgG1 levels of groups of mice (n = 6) immunized with (d) 10 μg, (e) 20 μg or (f) 30 μg of BM32 prior to (grey bars) and after (black bars) immunization, towards preS and synthetic preS overlapping peptides P1–P8 (x-axes). Results represent medians ± interquartile ranges from triplicate determinations.