Fig 5. Longitudinal Progressive Ratio (PR) Results for HdhQ111/+ animals.
PR testing of motivation demonstrated no statistically significant differences in performance between HdhQ111/+ and wild type animals at any age or reward size considered. However, animals were able to reach higher ratios of attainment at larger reward sizes and at higher break points. Data are shown for a total of 16 mice, 7 HdhQ111+ and 9 wild type. Data are shown as the average number of responses made over 3 days of testing, for each reward size. Error bars represent ± standard error of the mean. * p<0.05, ** p<0.01, *** p<0.001.