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| Pharmacokinetic parameters measured | |||
|---|---|---|---|
| Dose (mg/kg) | Tmax (h) | Cmax (ng/mL) | AUC (ng/mL*h) |
| 10 | 2.5 | 415 ± 20% | 1,780 ± 18% |
| 100 | 6 | 3,910 ± 20% | 32,900 ± 36% |
| 300 | 7 | 7,010 ± 32% | 60,900 ± 33% |
Abbreviations: time to reach the maximum observed plasma concentration (Tmax), maximum observed plasma concentration (Cmax), area under the concentration versus time curve (AUC).
