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. 2016 Oct 4;13(10):e1002138. doi: 10.1371/journal.pmed.1002138

Table 5. Correlation of the observed survival or antimalarial activity versus modeled maximal effect relationship.

Correlation for survival (R2) Correlation for antimalarial activity (R2)
AUC 0.96 0.88
C max 0.85 0.91
Time above threshold 0.96 0.97

R2 = correlation between observed and predicted activity. Abbreviations: area under the concentration versus time curve (AUC), maximum observed plasma concentration (Cmax).