Table 5. Correlation of the observed survival or antimalarial activity versus modeled maximal effect relationship.
Correlation for survival (R2) | Correlation for antimalarial activity (R2) | |
---|---|---|
AUC | 0.96 | 0.88 |
C max | 0.85 | 0.91 |
Time above threshold | 0.96 | 0.97 |
R2 = correlation between observed and predicted activity. Abbreviations: area under the concentration versus time curve (AUC), maximum observed plasma concentration (Cmax).