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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Biomaterials. 2016 Sep 6;108:168–176. doi: 10.1016/j.biomaterials.2016.09.004

Figure 2. NP-CpG control established leishmaniasis.

Figure 2

BALB/c mice were infected with 5×104 late stationary phase L. (V.) panamensis promastigotes. After lesions developed, mice were injected perilesionally twice a week for 2 weeks with PBS, 64 μg NP-CpG, dose-matched free CpG (93 ng), or 64 μg empty NP. (A) Lesion progression was monitored by weekly measurements of feet. (B) Three weeks post-treatment, mice were euthanized, and parasites were quantified in lesions by limiting dilution. Data are representative of 3 independent experiments. n=5–6; *p<.05; **p<.01.