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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Biomaterials. 2016 Sep 6;108:168–176. doi: 10.1016/j.biomaterials.2016.09.004

Figure 3. NP-CpG regulates cytokine responses in L. (V.) panamensis-infected mice.

Figure 3

Mice with established lesions were injected perilesionally twice a week for 2 weeks with PBS, 64 μg CpG-NP, dose-matched free CpG (93 ng) or 64 μg empty NP. Two days after the end of treatment, dLN cells were harvested and stimulated with Soluble Leishmania Antigen (SLA) and (A) IFNγ, (B) IL-17, (C) IL-10 and (D) IL-13 levels were determined by ELISA. Data are representative of 3 independent experiments. Bars display group mean with standard error. n=3–5;*p<.05; ***p<.001.