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(R)-DOI induces 5-HT2Areceptor internalization within 5-HT2A(+) cells: A,B) 40 × view of 5-HT2A-IR of deep layer V in prelimbic cortex of control (A) and treated (B) sections. C,D) 10 × view of 5-HT2A-IR in the lateral orbital cortex and agranular insular cortex (+ 4.2 mm from bregma) is shown in control (C) and treated (D) sections. E,F) 10 × view of orbital cortex showing overlay of 5-HT2A-IR (red) and Gad67-IR (green) in control (E) and treated (F) sections.
