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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Biomech Model Mechanobiol. 2016 Apr 4;15(6):1601–1618. doi: 10.1007/s10237-016-0785-2

Figure 10.

Figure 10

Sensitivity analysis of the radial growth time constant in relation to volumetric growth and flow parameters. Radial growth time constants are 5 (black), 10 (red), 20 (green), and 30 (blue) days. (A,B) For a fixed value of circumferential growth rate, frequency and contractility increase as radial growth rate decreases. (C,D) Shear stress is continually maintained regardless of the radial growth rate, and circumferential stress is always restored but reaches homeostasis slower as radial growth rate decreases. (E,F) Unloaded thickness and midwall diameter experience progressively larger increases as radial growth rate decreases. The larger increase in diameter occurs to compensate for the slower radial growth rate in the process of restoring circumferential stress to homeostasis. (G,H) Ejection fraction and average outflow rate are decreased as the radial growth rate increases.