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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Biomech Model Mechanobiol. 2016 Apr 4;15(6):1601–1618. doi: 10.1007/s10237-016-0785-2

Figure 7.

Figure 7

Change in contractile and mechanical parameters following acute contractile adaptation in response to a sustained increase in afterload. (A,B) Contractile frequency and systolic contractility increase following mechanical perturbation in order to restore shear stress. (C) Shear stress is restored to the homeostatic value following contractile adaptation. (D) Circumferential stress is reduced but not restored by contractile adaptation. (E) ESD is decreased due to the increase in systolic contractility, which in turn increases the ejection fraction. (F) Average outflow is nearly restored to the pre-perturbation rate following contractile adaptation.