Table 2.
Patient characteristics during the 48 h following randomization
| Variables | Continuous control of P
cuff
n = 18 |
Routine care n = 18 |
p |
|---|---|---|---|
| Ventilatory modea | >0.99 | ||
| ACV | 13 (72) | 13 (72) | |
| PSV | 9 (50) | 10 (56) | |
| Mean P peak (cmH2O) | 31 (21, 35) | 30 (24, 34) | 0.64 |
| Mean PEEP (cmH2O) | 7 (5, 9) | 6 (5, 8) | 0.73 |
| Mean FiO2 | 0.45 (0.40, 0.50) | 0.40 (0.40, 0.50) | 0.41 |
| Number of tracheal suctions | 6 (5, 7) | 6 (6, 7) | >0.99 |
| Sedation | 12 (67) | 14 (78) | 0.50 |
| Ramsay score | 5 (3, 6) | 4 (3, 6) | 0.86 |
| Neuromuscular blocking agent use | 1 (6) | 0 (0) | >0.99 |
| Head-of-bed position <30° | 4 (22) | 6 (33) | 0.50 |
| Fiberoptic bronchoscopy | 2 (11) | 2 (11) | >0.99 |
| Transport outside the ICU | 0 (0) | 1 (6) | >0.99 |
| Aerosolized medication | 2 (11) | 2 (11) | >0.99 |
| iNO | 2 (11) | 1 (6) | >0.99 |
| Quantity of enteral nutrition (mL/day) | 1000 (500, 1500) | 1000 (875, 1125) | 0.31 |
| Gastric residual volume (mL) | 0 (0, 61) | 0 (0, 100) | 0.52 |
| Vomiting | 2 (11) | 2 (11) | >0.99 |
| Prokinetic drugs | 1 (6) | 1 (6) | >0.99 |
| Stress ulcer prophylaxis or treatment | 16 (89) | 16 (89) | >0.99 |
Data are number of patients (%) or median (Interquartile range)
P cuff cuff pressure, ACV assist–control ventilation, PSV pressure support ventilation, P peak peak pressure, PEEP positive end-expiratory pressure, FiO 2 fraction of inspired oxygen, i NO inhaled nitric oxide
aSome patients received two ventilator modes during continuous control of P cuff, or during routine care