Table 1. General characteristics of the subjects.

Characteristics	Osteosarcoma patients (n = 358)	Controls (n = 402)
Age of diagnosis (median, years)	18.0 (6.0–58.0)	20.0 (12.0–59.0)
Gender, n (%)
Male	216 (60.3)	241 (60.0)
Female	142 (39.7)	161 (40.0)
Tumor location, n (%)
Long tubular bones	258 (72.1)
Axial skeleton	100 (27.9)
Metastasis, n (%)
Yes	105 (29.3)
No	253 (70.7)

SD, standard deviation.