Table 3. Allele distributions of three SNPs in IL16 between osteosarcoma patients and controls.
Polymorphisms | Osteosarcoma patients (%) | Controls (%) | Crude OR | Adjusted OR (95% CI)† | Adjusted P value† |
---|---|---|---|---|---|
rs4778889 | |||||
T | 557 (77.8) | 620 (77.1) | 1.00 (Ref) | 1.00 (Ref) | |
C | 159 (22.2) | 184 (22.9) | 0.96 (0.76–1.22) | 0.96 (0.76–1.23) | 0.76 |
rs11556218 | |||||
T | 504 (70.4) | 621 (77.7) | 1.00 (Ref) | 1.00 (Ref) | |
G | 212 (29.6) | 183 (22.8) | 1.43 (1.13–1.80) | 1.44 (1.14–1.81) | 0.002 |
rs4072111 | |||||
C | 560 (78.2) | 616 (76.6) | 1.00 (Ref) | 1.00 (Ref) | |
T | 156 (21.8) | 188 (23.4) | 0.91 (0.72–1.16) | 0.91 (0.72–1.16) | 0.45 |
SNPs, single nucleotide polymorphisms; OR, odds ratio; CI, confidence interval.
†Adjusted by age and gender.